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Exosome DNA & RNA

Exosomes are extracellular membrane vesicles (EVs) with a diameter of 30-200 nm secreted by various cells. Exosomes are commonly found in a variety of body fluids and their contents are rich in proteins, lipids and nucleic acids. They play an important role in intercellular information exchange, mainly involved in immune antigen presentation, neurotransmitter transmission, lipid metabolism and cell signalling, and are closely associated with the onset, development, treatment and prognosis of many diseases.


The main principle of these kits is the design and modification of resins that specifically bind to exosomes based on the membrane structure of exosomes (lipid bilayer), thus enabling the extraction and purification of exosomes by binding to components of the exosome lipid bilayer with little or no binding to other proteins in the sample. Exosome DNA can be easily and rapidly purified and eluted using the spin column method and can be used directly in downstream applications such as real-time PCR, expression array assays, and NGS.


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